Alex & Stewie of "Family Guy"

(credit: The CW Podsquad)

Brandee & Brian of "Family Guy"

(credit: The CW Podsquad)

Jodi & Maggie Simpson of "The Simpsons"

(credit: The CW Podsquad)

Joe & Catherine Chandler (Kristin Kreuk) of "Beauty and the Beast"

(credit: The CW Podsquad)

Justin & Dr. Zoe Hart (Rachel Bilson) of "Hart of Dixie"

(credit: The CW Podsquad)

Mariana & Elena (Nina Dobrev) of "The Vampire Diaries"

(credit: The CW Podsquad)

Michael & Homer Simpson of "The Simpsons"

(credit: The CW Podsquad)

OJ & Dean Winchester (Jensen Ackles) of "Supernatural"

(credit: The CW Podsquad)

Sierra & Damon (Ian Somerhalder) of "The Vampire Diaries"

(credit: The CW Podsquad)

Tyler & Oliver Queen (Steve Amell) of "Arrow"

(credit: The CW Podsquad)